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Vertical Mini
AURA MiniTM Cabinet is made in Italy for Cruma by Euroclone under the brand Bioair and is supplied in one compact size only (895 mm). These state of the art compact down-flow cabinets, provide an ultimate cleanliness Class 100 work area where the highest safety for the products is achieved. The internal design, the air flow aerodynamics, the special H14 filter and the Filtrete®exhaust filter (or prefilters) guarantees the highest performances at the most stringent safety levels and operator comfort. Two operating modes are available: inward air barrier and outward air barrier. INWARD air barrier. In this configuration an air barrier flows through the front opening and is recirculated with the downflow air by a motor blower. 70% of the air is returned to the work area through the main HEPA filter and 30% is exhausted into the environment through a Filtrete®exhaust filter with gravimetric efficiency of 99% on 3μm particles. In this configuration an excellent product protection is ensured, aswell as an outstanding containment. OUTWARD air barrier. In this case the air is sucked through the Filtrete®prefilter, mixed with the incoming recirculating air and then filtered through the main HEPA filter into the work area: here 30% of the air is exhausted through the front opening and 70% is recirculated. This configuration ensures the highest product protection. In the INWARD configuration this unit can easily be used as an “active PCR” cabinet for DNA carry over blocking.
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check-ups and validations
International standards for the design and operation of laminar flow cabinets, clean rooms and related systems, such as BS 7989:2001, EN-12469 and EN-ISO-14644 (all of which are observed in CRUMA models) recommend that cabinets should be inspected once a year.
This inspection should really be a validation or qualification, i.e., it should be carried out in accordance with a protocol created by CRUMA (PCO 002/03 Protocol of Operational Qualification) and based on that set out in the above standards.
In Spain, these qualification operations will have to be performed by ENAC (National Accrediting Agency) -certified companies or any of its accredited offices, and authorized by CRUMA, who is responsible for advising them on the implantation of the qualification
protocol. In practice, CRUMA has its own laminar flow cabinets validation service performed by companies that are certified and have proven experience in the field.
Contact CRUMA at Telephone
+ 34 902 370 700 or by e-mail. Contact CRUMA for further information.
This inspection should really be a validation or qualification, i.e., it should be carried out in accordance with a protocol created by CRUMA (PCO 002/03 Protocol of Operational Qualification) and based on that set out in the above standards.
In Spain, these qualification operations will have to be performed by ENAC (National Accrediting Agency) -certified companies or any of its accredited offices, and authorized by CRUMA, who is responsible for advising them on the implantation of the qualification
protocol. In practice, CRUMA has its own laminar flow cabinets validation service performed by companies that are certified and have proven experience in the field.
Contact CRUMA at Telephone
+ 34 902 370 700 or by e-mail. Contact CRUMA for further information.
The protocols (PCO 00/03 and PCO 002/03) currently employed by CRUMA in validation and checkup operations are in general comprised of the following procedures:
• Visual inspection to determine state of conservation.
• Airflow rate and uniformity test.
• Filter frame case air-tightness test.
• Filter medium air- tightness test.
• Airflow distribution test (Smoke test).
• Particle count and class determination.
• Temperature.
• Relative humidity.
• Electrical test.
Once the above procedures have been performed, a technical report containing the following points is issued:
• Description of the work procedures performed.
• Copy of the current calibration certificates of each measurement unit used.
• Diagram of the cabinet with the coded location of sample points.
• Results obtained.
• Certificate of cabinet performance
• Description of the work procedures performed.
• Copy of the current calibration certificates of each measurement unit used.
• Diagram of the cabinet with the coded location of sample points.
• Results obtained.
• Certificate of cabinet performance
